A macro-dose experience unfolds in stages, guiding you through deep introspection and emotional release:
1️⃣ Onset (15-30 min after ingestion)
2️⃣ Dissociation (30-60 min)
As the ketamine takes effect, you’ll feel a gradual shifting of awareness. Sensory perceptions may soften, and you might notice:
🔹 A sense of heaviness or floating, as if gravity is shifting.
🔹 A warm, soothing calmness washing over your body.
🔹 Thoughts slowing down and becoming more fluid.
🔹 A feeling of detachment from stress, anxiety, or daily concerns.
At this stage, it’s best to close your eyes, relax, and allow the experience to unfold naturally.
This is the peak of the macro-dose experience, where everyday thoughts fade, and you enter a dreamlike, dissociative state.
🔹 A detachment from your physical body—it may feel distant or weightless.
🔹 Time distortion—minutes may feel like hours, or time may cease to exist altogether.
🔹 The feeling of “watching yourself” from an outside perspective—a shift that helps process emotions without attachment.
🔹 Reduction in fear and emotional resistance—allowing suppressed memories or emotions to surface without distress.
🔹 Ego-dissolution—a temporary release from personal identity and self-referential thinking.
This phase disrupts the rigid mental loops that contribute to depression, trauma, and anxiety, allowing you to step outside of conditioned thought patterns and view your life from a new perspective.
3️⃣ Expanded Awareness (60-90 min)
4️⃣ Integration (90 min - 3 hrs)
As the dissociation deepens, powerful insights may emerge. This is where the true healing potential of macro-dosing happens.
🔹 Visions or symbolic imagery—your mind may present meaningful visuals related to your healing journey.
🔹 Emotional processing—you may recall past events with new understanding, releasing trauma in a safe, detached way.
🔹 Cosmic or spiritual experiences—some describe feelings of universal connection, deep peace, or profound oneness.
🔹 Rewiring of thought patterns—many experience a sudden realization of how to move past emotional blocks.
🔹 Moments of surrender and profound acceptance, leading to a deep sense of relief and renewal.
Not everyone has a visionary or mystical experience, but most people emerge with a deeper understanding of themselves and their emotions.
As the effects fade, you’ll return to a clear, grounded state—but often with a sense of peace, clarity, and emotional lightness that lingers long after the session.
🔹 A feeling of mental reset, as if the brain has been refreshed.
🔹 Lasting emotional relief—many feel like a weight has been lifted.
🔹 Increased openness and mental flexibility—making it easier to adopt new perspectives and behaviors.
🔹 A sense of gratitude, acceptance, and deeper self-compassion.
This afterglow effect can last for days or even weeks, making it an ideal window for self-reflection, journaling, or therapy.